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Jose Azocar, MD

Education

Dr. Azócar obtained his MD from the Central University Medical School in Caracas Venezuela, and his MSc and a Doctorate in Science from Harvard University. He did his postdoctoral training in oncology and hematology at Boston and Brown universities.
Dr. Azócar is currently Medical Director at Northgate Medical, Springfield MA. He has served at various other hospitals as a primary care and internal medicine physician.

Research

Clinical Research SITE: Principal Investigator
  1. Therapeutic Vaccine for HIV Clinical Trial (Phase III REMUNE). Immuno Research Corporation and Northgate Medical, Springfield, MA (1996-1999)
  2. Wings. Pegasys/HCV/Roche: 2001- present
  3. Takeda/ Actos: 2001- present
  4. HCV/Recap/ Sherring: 2000-present
  5. Clinical Research SITE: Associated Investigator: Community Research Initiative of New England
Publications
  1. Azocar, J., Essex, M., Susceptibility of Human Cell Lines to Feline Leukemia Virus and Feline Sarcoma Virus. Journal National Cancer Institute, 1979 Nov.; 63(5): 1179: 84.
  2. Azocar, J., Essex, M., Incorporation of HLA Antigens into the Envelope of RNA Tumor Viruses Grown in Human Cells. Cancer Res., 1979, Sep.; 39(9): 3388-91.
  3. Azocar, J., Essex, M., Feline Oncornaviruses: Replication in Human Cells. In: Advances in Leukemia Research. Lapin and Blakeslee, eds. Elsevier/North Holland, Inc. 1979: 179-84.
  4. Azocar, J., Essex, M., Interaction of Feline Leukemia Virus with Lymphoid Cells. In: Virus Lymphocyte Interactions: Implications for Disease. Profit, M., ed. Elsevier/North Holland, Inc. 1979: 179-89.
  5. Azocar, J., McLane, M.F., Essex, M., Neutralization of Feline Retroviruses with Antisera to Normal Cells. In: Feline Leukemia and Sarcoma Viruses. Essex, M., ed. Elsevier/North Holland, Inc. 1980: 481-7.
  6. Gazit, E., Azocar, J., Mahoney, R., Watson, A., Dubey, D., Essex, M., Yunis, E., Modulation of Antigen Expression on Lymphoblastoid Cell Lines. Transplant Proc.1981 Mar; 13(1pt2): 1002-4.
  7. Dubey, D., Staunton, D., Azocar, J., Stux, S., Essex, M., Yunis, E., Natural Killer Activity Against Retrovirus Infected Cells: Dichotomy in NK Sensitivity of Infected T and B Cells: Clin Immunol Immunopathol 1982 May; 23 (2): 215-23.
  8. Moake, J.L., Rudy, C.K., Troll, J.H., Weinstein, M.J., Colannino, N.M., Azocar, J., Seder, R.H., Hong, S.L., Deykin, D., Unusually Large Plasma Factor VIII:von Willebrand Factor Multimers in Chronic Relapsing Thrombotic Thrombocytopenic Purpura. NEJM, 1982 Dec 2; 307 (23): 1432-35.
  9. Azocar, J., Yunis, E.J., Essex, M., Sensitivity of Human Natural Killer Cells to Hyperthermia. Lancet, 1982 Jan 2; 1 (8262): 16-7.
  10. Lee, T.H., Essex, M., de Noronha, F., Azocar, J., Neutralization of Feline Leukemia Virus with Feline Antisera to Leukocyte Alloantigens. Cancer Res 1982 Oct; 42(10): 3995-93.
  11. Azocar, J., Essex, M., Watson, A., Gazit, E., Anderson, D., Yunis, E.J., Changes in the Expression of HLA and Beta 2 Microglobulin by cultures Lymphoid Cells. Hum Immunol 1982 Dec; 5(4): 283-93.
  12. Romet-Lemonne, J.L., McLane, M.F., Elfassi, E., Haseltine, W.A., Azocar, J., Essex, M., Hepatitis B Virus Infection in Cultured Human Lymphoblastoid Cells. Science 1983 Aug 12; 221(4611): 667-9.
  13. Azocar, J. Essex, M., Yunis, E.J., Cell Culture Density Modulates the Incorporation of HLA Antigens by Enveloped Viruses. Hum Immunol 1983 June; 7 (2): 59-65.
  14. Azocar, J., Anti-Myeloid-Cell Antibody in Procainamide-Induced Agranulocytosis (letter). Lancet 1984 May 12; 1 (8385): 1069-70.
  15. O’Daly, J.A., Azocar, J., Immunological Alterations in Chagas Disease. Chandra, R.K., ed. In: Critical Reviews in Tropical Medicine. Plenum Publishing. 1984; 187-99.
  16. Azocar, J., Linares, J., Essex, M., Distribution of Antibodies Against the Human T-Cell Leukemia Virus in Healthy Venezuelan Adults Acta Cient, Venezuela 1985; 36 (2): 170-2)
  17. Correnti, M., Pena, M., Mosca, W., Azocar, J., Tapia, F.J., Immunocytochemical Analysis of Lymphocyte Subpopulation in Healthy Individuals in Venezuela. Acta Cient, Venezuela 1986; 37(2): 221-2.
  18. Azocar, J., Martinez, C., McLane, M.F., Allan, J., Essex, M., Lack of Endemic HIV Infection in Venezuela. AIDS Res Hum Retroviruses 1987 (summer); 3(2): 107-8.
  19. Azocar, J., Menendez, C.U., Ramirez, J.L., Hernandez, R., Acosta, H., Reumann, W., Rincon-Moralez, F., Estevez, J.A., Detection of Human Papilloma Virus Sequences in Uterine Cervix Lesions in Venezuela. Acta Cient Venezuela1988; 39(2): 171-4.
  20. Lechin, F., Van Der Di, J.S., Azocar, J., Amat, J., Vitelli, J., Martinez, C., Lechin, S., Cabrera, A., Cardenas, M., Villa, S., Stress Immunology and Cancer: Effect of Psychoactive Drugs. Arch Venez de Farmacol y Terapeu. 1987; 3: 107-8.
  21. Rincon, M.F., Ramirez, J.L., Menendez, C., Azocar, J., Papilloma Virus DNA Sequences in Invasive Cervical Carcinoma. Arch Venez de Farmacol y Terapeu 1988; 7:24-32.
  22. Azocar, J., Abad, S.M., Acosta, H., Hernandez, R., Gallegos, M., Pifano, E., Blanch, R., Kramar, A., Prevalence of Cervical Dysplasia and HPV Infection According to Sexual Behavior. Int’l J Cancer 1990 Apr 15; 45(4): 622-5.
  23. Roman-Roman, S., Ferradini, L., Azocar, J., Genevee, C., Hercend, T., Triebel, F., Studies on the Human T Cell Receptor Alpha/Beta Variable Region Genes. I. Identification of 7 Additional V Alpha Subfamilies and 14 J Alpha Gene Segments. Euro J Immunol 1991 Apr; 21(4): 927-33.
  24. Ferradini, L., Roman-Roman, S., Azocar, J., Michalaki, H., Triebel, F., Hercend, T., Studies on the Human T Cell Receptor Alpha/Beta Variable Region Genes. II. Identification of Four Additional V Beta Subfamilies. Euro J Immunol 1991 April 21(4): 935-42.
  25. Ferradini, L., Roman-Roman, S., Azocar, J., Avril, M.F., Triebel, F., and Hercend, T., Analysis of T Cell Receptor Alpha/Beta Variability in Lymphocytes Infiltrating a Melanoma Metastases. Cancer Rsch 1992. 52: 4649-54.
  26. James O. Kahan et al. Evaluation of HIV-1 Immunogen, an Immunologic Modifier, administered to patients infected with HIV having 300 to 549x10/6 CD4 cell counts. JAMA, 2000; 17:2193-2202.
  27. Azocar J, Clavijo Olga, Yunis EJ. MHC Class II Genes in HCV viral clearance of Hepatitis C Infected Hispanic patients. Hum Immun. In Press.