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Natural History: HCV symptoms, disease progression and management..

 

      General

o   1612. Relationship of Iron [Fe] and HFE genetic variations to progression and outcomes of advanced chronic hepatitis C in the HALT-C Trial.

o   1613. Aging of Hepatitis C Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression. (updated Nov 5, 2009)

o   1617. Incidence of end-stage liver disease and death among 585 HIV/HCV coinfected adults according to baseline fibrosis stage. (updated Nov 5, 2009)

o   1620. Validation of a panel of genetic markers (CRS7) in predicting cirrhosis, fibrosis progression (FP) and clinical outcomes in patients with chronic hepatitis C (CHC) in the HALT-C trial.

o   1622. Insulin Resistance and Hepatic Steatosis are Both Independently Associated with Advanced Hepatic Fibrosis in Chronic Hepatitis C Infection: Analysis of the ACHIEVE 1 and ACHIEVE 2/3 Cohorts

o   1625. Serum fibrosis markers are associated with clinical outcomes and histological progression in patients with chronic hepatitis C (CHC) and advanced fibrosis. 

o   1626. Chronic Hepatitis C Infection is Associated with Lower Rates of Hospitalization for Coronary Heart Disease.

o   1627. Hepatic Impairment Measured by Quantitative Tests of Liver Function (QLFTs) Predicts Clinical Outcome in Patients with Advanced Fibrosis: Results from the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) Trial.

o   1650. Long-term evaluation of fibrosis by Transient Elastography in patients clearing HCV on antiviral therapy.

o   1655. Quantitative HCV core antigen and HCV-RNA kinetics in HCV infected patients over a period of up to 8 years.

o   1656. The Extent of Liver Fibrosis Measured Using Transient Elastometry Predicts Mortality in HIV Patients with Liver Cirrhosis.

o   1657. Amino acid substitutions in the hepatitis C virus core region were induced by aging and severe hepatic fibrosis.

o   1658. Semen Characteristics In Hepatitis C Virus (HCV) Infected Patients. Relationship Between Semen Characteristics And Assisted Reproduction Technologies (ART) Practice. (updated Nov 5, 2009)

o   1659. Excessive alcohol intake drastically impacts transplant-free survival: a longitudinal study in HCV cirrhotic patients (updated Nov 9, 2009)

o   1663. Prediction of HCV-related mortality in Belgium using a mathematical modeling approach: impact of current treatment practice and different scenarios improving screening, access to treatment and treatment efficacy.

 

o   Acute HCV

§  1619. Natural clearance of hepatitis C virus (HCV) RNA in chronic HCV carriers: A long-term cohort study in an endemic area of HCV infection in Japan.

§  1662. Early spontaneous resolution of acute hepatitis C depends on the HCV genotypes and the levels of HCV RNA.

 

o   Biopsy

§  1629. Paired Biopsies Illustrate Racial Differences in Fibrosis Progression in HCV Patients.

§  1630. Age, Insulin Resistance and Steatosis are Independent Risk Factors for Fibrosis Progression in Untreated Patients with Mild Chronic Hepatitis C: A Prospective Study with Repeat Biopsies. (updated Nov 13, 2009)

§  1639. Hepatic fibrosis regression in the setting of persistent viremia in chronic hepatitis C: a dual biopsy study.

§  1654. Diagnosis of occult HCV infection without performing a liver biopsy.

 

o   Quality of Life

§  1644. Resilience affects the quality of life in patients with chronic hepatitis C. (updated Nov 5, 2009)

§  1645. Self-reported cognitive symptoms are commonly associated with underlying neurocognitive impairment in hepatitis C infected patients referred for antiviral treatment. (updated Nov 5, 2009)

 

o   Women

o   1615. Early loss of exposure to Estrogens is critical in determining entity of fibrosis and response to IFN in women with hepatitis C.

o   1631. Hepatitis C and menopause: interplay of age, gender, HCV replication and activity in progression and consequence for therapy. (updated Nov 13, 2009)